Daga cikin kwayoyi da suke ji da kuma haddasa tashin hankali, daya daga cikin wurare na farko shine meldonia, aikin da ke cikin jiki wanda ba likitoci da marasa lafiya kawai ba, har ma 'yan wasa, sojoji da mutanen da ba su da matsaloli na musamman. Abin da ya faru da meldonium, abin da ya faru bayan an karɓa, za mu ci gaba da kara.
Meldonius - menene wannan magani?
Meldonium mai kirki (Mildronate - sunan kasuwancin miyagun ƙwayoyi) ya ci gaba a cikin shekaru bakwai na karni na karshe daga masanin kimiyyar Latvia Kalvinshem kuma an fara amfani da shi a aikin noma don tada girma daga dabbobi, kaji da tsire-tsire. Maganin abu ne mai ma'anar gamma-butyrobetaine, wani ƙaddarar carnitine, wani abu da aka samar a cikin jikin don manyan ayyuka. Ɗaya daga cikin ayyuka na carnitine yana da alaka da matakai na rayuwa wanda ya haɗa da hawa kayan acid a jikin tsoka, inda fats sun shiga makamashi.
Tun shekarar 1984, an yi nazarin aikin da aka yi a jikinsa, har zuwa yau, an fara amfani da shi a magani. A shekarar 2012, an hada shi a jerin sunayen magunguna masu guba a Rasha, kuma a shekara ta 2015 hukumar kare hakkin bil adama ta duniya ta dakatar da wannan miyagun ƙwayoyi domin amfani da shi a wasanni na sana'a (masu bincike na kasashen waje sun yanke shawara cewa meldonium yana karewa). Yau ana amfani da miyagun ƙwayoyi a cikin kantin magani a wasu nau'i uku: capsules, syrup da bayani don injections.
Meldonium - ka'idar aikin
Za mu gano yadda tasirin muldonium ya shafi kyallen takalmin jikin. Tun da wannan fili, kasancewa kamar maganin gamma-butyrobetaine, zai iya haifar da raguwa a cikin kira na carnitine, wannan yana haifar da raguwa a cikin hanyar sauya ƙwayoyi zuwa jikin tsoka. Wannan sakamako yana da mahimmanci a lokacin raunin oxygen wanda tsohuwar ƙwayar zuciya ta samu, tun da ciwon da ake amfani dashi na acid mai yawa da kuma rashin daidaituwa na oxygen, rashin isasshen abuwan iskar gas da aka samo shi ne tare da tarawar kwakwalwa masu lahani ga zuciya.
Tare da raguwar ƙwayar ƙarfin mikiyar acid a karkashin jagorancin meldonia wani karuwa a cikin yawan kuzari na carbohydrates na faruwa, wanda ke buƙatar rashin amfani da oxygen. Godiya ga wannan, ingantaccen tsari na ATP (tushen makamashi), mayar da daidaituwa a tsakanin bukatun sel a oxygen da kuma ainihin sakonta tare da jini, ya kawar da tarawar mahaɗar haɗari a cikin kwayoyin.
Bugu da kari, tare da waɗannan matakai, an ƙara karuwa a cikin abun ciki na gamma-butyrobetaine, wanda ke da kayan haɓaka, yana kiyaye. Wannan ya kunshi shakatawa mai tsabta na jini, yalwata ƙarancin jini, inganta jinin jini, wanda ya fi dacewa ga yankunan da ke cikin ƙasa.
Mun lissafa dukkan abubuwan da aka samu tare da karɓar meldonia:
- Ƙirƙirar aiki;
- antihypoxic;
- Hanyar sarrafawa;
- anti-anginal;
- inganta cigaban jini;
- sakamako na tonic;
- ƙara ƙarfin hali, aiki aiki;
- sabuntawa na samar da wutar lantarki a cikin gajeren lokaci;
- rage yawan tsananin bayyanar cututtuka da ta jiki;
- daidaituwa na rigakafi na salula;
- kawar da maye gurbin ciwo.
Mene ne amfani da meldonium?
Idan aka ba da sakamako akan jiki meldonium yana da, yana da kyau a yi amfani dashi ga yanayin da ke hade da rashi oxygen kuma ƙara ƙarfafa. Sau da yawa, don dalilai na likita, wannan magani ba babban magungunan ƙwayoyi ba ne kuma ba'a amfani dashi ba, amma an tsara shi a matsayin ɓangare na cikakkiyar magani. Meldonia shaida a magani yana da wadannan:
- na kullum zuciya rashin cin nasara;
- cututtukan cututtukan zuciya ne;
- ƙananan ƙananan haɗari;
- angina pectoris;
- dystrophy na damuwa;
- rushewa na aiki na tsarin jijiyoyin jini na yanayin aiki a lokacin samari;
- neurocirculatory dystonia a cikin matasa;
- bugun jini na kwakwalwa;
- rashin lafiya na cerebrovascular;
- cututtukan ido tare da raunin jini a wurare dabam dabam a cikin ido;
- ciwon jini a cikin ɓoye na ido;
- thrombosis na tsakiya tsakiya ko rassan ido ido;
- retinopathy na ciwon sukari ko hypertensive asalin;
- Abstinence barasa;
- ilimin cututtuka na numfashi, tare da rashawar oxygen (ciwon daji na fata, mashayanci na asali);
- ragewa cikin tunanin mutum ko aikin jiki na asali;
- Bayanai bayan kammalawa bayan wasu ayyukan tsoma baki.
Meldonium - aikace-aikace
Yi amfani da meldonium a Allunan, syrup ko injection (intravenously, intramuscularly ko parabulbar - gabatarwa ta hanyar fata na ƙwalƙashin ƙananan). Dosages, multiplicity da kuma tsawon lokaci na liyafar an ƙayyade ɗaya, dangane da ganewar asali da kuma tsananin da yanayin haƙuri. Yana da kyau a fahimci cewa ba za a iya ɗaukar miyagun ƙwayoyi ba tare da magungunan likita ba, saboda tsangwama na wucin gadi a cikin aiki na zuciya, cin zarafin ƙare da aka kafa ta yanayi zai iya haifar da mummunar sakamako.
Meldonium ga 'yan wasa
Sanin abin da muldonia zai iya samu a jiki, ya zama abin da ya sa 'yan wasa suke amfani da ita. Ana amfani da kayan aiki a kowane nau'i na wasanni: wasanni, wasan tennis, biathlon, kokawa, gina jiki, iyo da sauransu. Ana amfani da mildronate a wasanni don cimma sakamakon da ke faruwa:
- rigakafin haɗuwa a cikin kwayoyin samfurori masu guba marasa acid wanda ba a tabbatar da shi ba;
- kulawa da makamashi na makamashi a cikin kwayoyin zuciya da kuma inganta rayuwar su;
- ƙara yawan kwangila;
- inganta abinci mai gina jiki;
- Ƙara girma da tasirin horo;
- rage yawan gajiya;
- inganta gyaran jiki bayan motsa jiki.
Matsayin yau da kullum na miyagun ƙwayoyi ga 'yan wasa shi ne mintina 15 na kowace kilogram na nauyin nauyin nau'i a cikin nau'i nau'i. An bada shawarar yin amfani da magani don minti 30-40 kafin fara aikin motsa jiki. Hanyar shiga shi ne daga wata zuwa waccan watanni, bayan haka ya kamata ka yi hutu don akalla watanni daya. Kafin samun gasar meldonium an karɓa a cikin makonni 2-3, kuma a lokacin gasar - ba fiye da kwanaki 14 ba. A wannan lokacin, an dakatar da miyagun ƙwayoyi a manyan wasanni, kuma masu halartar taron, waɗanda aka gano wannan abu a cikin jini, an kore su.
Meldonias a cikin Ciwon sukari
Kwanan nan, an yi amfani da launi na nau'i na nau'i na 2 da kuma irin su 1, bisa ga binciken da ya nuna yiwuwar abu don rage yawan glucose cikin jini. Bugu da kari, ƙin insulin ba zai kara ba. Sau da yawa tare da wannan cututtukan, an umarci miyagun ƙwayoyi tare da yin amfani da metformin guda ɗaya (wakili mai rage sukari daga ɗakin tsauni). Irin wannan magani, baya ga rage jini sugar, yana samar da wadannan sakamakon:
- rigakafin cututtuka da rashin asarar jin zafi;
- goyon bayan zuciya tsoka, sabuntawa na matakai na rayuwa a ciki;
- rigakafi na cigaban ciwon sukari da ciwon sukari, neuropathy da kiba;
- rigakafin lalacewar cututtuka.
Meldonias tare da arrhythmia na zuciya
Idan zuciyar tsokoki ta yi aiki ba daidai ba, haɗin zuciya na al'ada ya kakkarye - wani arrhythmia. A wannan yanayin, masana zasu iya bayar da shawarar meldonium, aikace-aikace a maganin da ke nuna sakamako mai kyau. Lokacin yin amfani da miyagun ƙwayoyi a cikin farfadowa mai mahimmanci, zai yiwu a cimma daidaituwa mai karko daga nauyin zuciya. Saboda shan miyagun ƙwayoyi a marasa lafiya, hadarin haɓakar angina pectoris , raguwar ƙananan ƙwayar cuta ne aka rage.
Meldonium daga matsa lamba
Meldonium, wanda tasirin jikinsa ya nuna kansa akan yanayin aiki na tsarin jijiyoyin jini, zai zama da amfani ga marasa lafiya da cutar hawan jini. Nazarin ya nuna cewa miyagun ƙwayoyi, tare da manyan cututtukan cututtuka (daga cikinsu akwai muhimmin tasirin maganin rage karfin matsalolin), yana taimaka wajen rage yawan ƙwayar cholesterol a cikin jini - wani dalilin da ya haifar da hawan jini. A wannan yanayin, ana iya bada shawarar yin amfani da marasa lafiya don amfani da ƙwayar meldonium intramuscularly.
Meldonium tare da barasa
Kyakkyawar meldonia daga gishiri , bayyanuwar bayyanar cututtuka a marasa lafiya da ciwon giya. Da miyagun ƙwayoyi ba wai kawai inganta lafiyar jiki ba, amma kuma yana hana farawa da sakamakon da ya haifar da haɗarin barasa a zuciya da kwakwalwa. Matsayi guda ɗaya a cikin wannan yanayin shine miliyon 500, wanda ya ɗauki sau 3-4 a rana don kwanaki 7-10. Ana gudanar da darussan warkewa a tsaka-tsakin na akalla watanni 1-2.
Meldoniy daga gajiya
A wasu lokuta, an halicci meldoniy na maganin gajiya mai tsanani wanda ya haɗta da ƙarfin tunanin mutum da tunanin mutum, da kuma lokacin da jiki ya ƙare saboda rashin lafiya. Da miyagun ƙwayoyi, wanda yana da tasiri mai kyau, yana taimaka wa jiki wajen magance matsaloli ba tare da lalacewa ga tsarin kwakwalwa ba, amma ya sake dawowa, kawar da rauni da damuwa.
Meldonium - sakamako masu illa
Bari mu tantance abin da sakamakon meldoniy zai haifar:
- overexcitation, tashin hankali;
- ciwon kai;
- dizziness;
- Muryar kunne a kunne;
- tremor;
- raunana hankali;
- jin tsoro;
- canji a cikin karfin jini;
- tachycardia;
- rashin tausayi a zuciya;
- fafatawa ko horarwa;
- dyspepsia;
- tari;
- dandano mai kyau a baki;
- bushe baki;
- ciwo na ciki;
- zawo;
- ƙwayoyin tsoka;
- kumburi;
- rashin halayen rashin lafiyan (rash, itching, Quincke's edema) da sauransu.
An yi amfani da manoma a ciki?
An gano cewa meldonium da Mildronate, tare da amfani da dadewa, suna jaraba ne a wasu mutane. Mafi mahimmanci shine mummunan sakamako na 'yan wasan da, bayan sun dakatar da yin amfani da miyagun ƙwayoyi, sun fara samun matsalolin halayyar kwakwalwa - rashin jin dadi ga horo ko gasar, gajiya mai rauni, rauni.
Meldonium - contraindications don amfani
Magani magani meldonium contraindications ga ganawa yana da wadannan:
- kowane mutum da hankali ga abubuwan da ke cikin miyagun ƙwayoyi;
- ƙãra matsa lamba intracranial;
- ƙwayar kofi ko rashin lafiya na asibiti, mai tsanani;
- ciki, lokacin shayarwa.
Meldonium - analogues na shiri
Idan ba zai yiwu a yi amfani da kwayoyi dauke da meldonium ba, ana iya amfani da analogues masu nuna irin wannan sakamako na likitancin magani tare da likita. Irin waɗannan maganin sun hada da:
- Dibikor;
- Vero-Riboxin;
- Binciken;
- Coenzyme Q10;
- Lipamid;
- Riboxin .