Gizon gwal yana ɓoye magunguna masu yawa wadanda ke tsara aikin aikin endocrine, gwaninta da ci gaban jiki. Ɗaya daga cikin waɗannan kwayoyin hormones shine somatotropin (somatropin). Ya maida hankali ne na musamman ga yara, matasa, mata da 'yan wasa.
Menene hormone da ke da alhaki?
A lokacin ƙuruciyar (har zuwa shekaru 20), an sake sakin magungunan sunadarai a cikin yawan adadi. Ya zama wajibi ne don ci gaban al'ada na ƙasusuwa masu tsayi, saboda haka wannan abu shine ake kira girma hormone girma hormone. Bayan shekaru 20, lokacin da tsarin ƙwayoyin ƙwayoyin cuta ya fara kafa, an rage yawancin aikinsa. Halin hormone (STH) ya haifar da wasu sakamako:
- kunnawa da kuma goyan bayan T-cell immunity;
- intensifies sweating;
- qara qarar halayen ligaments;
- rage jinkirin tsarin tsufa;
- inganta digestibility na alli a cikin hanji.
Sakamakon girma hormone akan metabolism
'Yan wasan suna mai da hankali ga STG saboda ikonsa na gaggauta haɓakar daji mai karfi da kuma gina tsoka. An samar da hormone cike da kwayoyin adenohypophysis (somatotrophs), dangane da tsarin kwayoyin sunyi kama da prolactin da lactin placental. A saboda wannan dalili, mata ma za su rike kulawar STH. Yana inganta silhouette, yana bada tallafi ga ligaments a yankin gland, yana taimakawa wajen kula da matasa da jiki mai kyau.
Ayyukan wani hormone somatotropic a kan matakai na rayuwa:
- haɓaka halayen gina jiki da kuma jinkirin lalatawarsu;
- ƙuntatawa ga shigar da nama na adipose;
- ƙara yawan glucose jini;
- rage yawan ƙwayar sodium da potassium daga jiki.
Turawa don girma hormone
Don daidaita ƙayyadadden abu a cikin tambaya, yana da muhimmanci a yi nazarin binciken binciken kwayoyin jini. Yadda ya kamata a ba da ruwa a kan wani kwayar halitta mai kama da kwayar halitta ta jikin jikin jikin mutum:
- Ranar kafin bincike, share duk kayan abinci mai kyau daga menu.
- A shawarwari tare da likita, dakatar da shan shan magani 24 hours kafin zuwa dakin gwaje-gwaje.
- A tsakar rana na nazarin, guje wa rikici da jiki. Girman hormone yayi girma bayan ƙarfin danniya.
- 12 hours kafin gudunmawar jini, kada ku ci, saboda haka yafi kyau yin bincike a safiya.
- Kada ku shan taba 3 hours kafin gwajin.
STG yana samuwa ne a yayin hawa a rana, yana canzawa a bayan bayanan ƙaddamarwa da sauran yanayi. Yana da shawara don bayar da gudunmawar jini sau da yawa kuma ya ƙididdige yawan adadin sakamakon. Abinda ke ciki na somatotropin ya dogara da jima'i:
- mata - har zuwa 8-10 ng / ml;
- maza - har zuwa 2-3 ng / ml.
Halin hormone girma shine al'ada a cikin yara
Yawan abu da aka kwatanta a cikin jinin yaron ya dace da shekarunsa, ana kiyasta yawan iyakar a lokacin balaga. Harshen tsire-tsire shi ne al'ada ta hanyar tsufa:
- har zuwa shekaru 3 - 0.43-3.03 ng / ml ga yara maza, 0.37-2.07 ng / ml ga 'yan mata;
- 3-6 shekaru - 0,1-1,9 ng / ml ga yara maza, 0,07-2,17 ng / ml ga 'yan mata;
- Shekaru 6-9 - 0.13-4.67 ng / ml ga yara maza, 0.13-2.77 ng / ml ga mata;
- daga 9 zuwa 10 - 0.07-0.27 ng / ml ga yara, 0.07-1.7 ng / ml ga 'yan mata;
- Shekaru 10-11 - 0.1-5.97 ng / ml ga yara, 0.07-4.07 ng / ml ga 'yan mata;
- Shekaru 11-12 - 0.13-9.7 ng / ml ga yara maza, 0.1-7.7 ng / ml ga 'yan mata;
- Shekaru 12-13 - 0.17-15.43 ng / ml ga yara maza, 0.1-6.83 ng / ml ga 'yan mata;
- Shekaru 13-14 - 0,13-8,57 ng / ml ga yara maza, 0,1-6,17 ng / ml ga 'yan mata;
- Shekaru 14-15 - 0.2-8.67 ng / ml ga yara maza, 0.1-6.77 ng / ml ga 'yan mata;
- Shekaru 15-16 - 0.23-10.13 ng / ml ga yara, 0.07-9.87 ng / ml ga 'yan mata;
- Shekaru 16-17 - 0.27-9.37 ng / ml ga yara maza, 0.2-10.57 ng / ml ga mata;
- Shekaru 17-19 - 0,23,73 ng / ml ga yara, 0,83-4,07 ng / ml ga 'yan mata.
Girman hormone ya taso
Rashin hankali na STH yana haifar da cututtuka mai tsanani da barazanar rayuwa. Idan an kara hawan hormone a cikin yara, gigantism yana tasowa. Ci gaba da yaron ya kara da kuma bambanta da bambanci daga alamomi. Hakazalika, gabobin ciki suna karuwa da girman. Tare da tsufa, hormone somatotropic wuce gona da iri yana kaiwa ga acromegaly da cututtuka masu kama da bayyanar cututtuka:
- thickening da thickening na fata;
- matsanancin gashi;
- tsawa mai tsanani;
- ƙara yawan abun ciki na epithelium;
- karin cholesterol da arteriosclerosis na jini;
- ciwon sukari mellitus ;
- rashi na alli a jiki;
- pathology na tsarin mai juyayi;
- ƙaddamar da siffofin fuska da sassa na jiki;
- migraines;
- rage aduity gani;
- kwakwalwa ;
- Gynecomastia;
- rashin wari;
- haɓakawa na juyayi;
- apnea;
- jima'i dysfunction;
- canje-canje ga ci abinci da ingancin barci.
Me yasa hormone girma ya karu?
Babban ma'anar matsalar da aka bayyana shi ne ƙwayar cutar gyuka, saboda haka an gano masu binciken endocrinologists a farkon gwagwarmaya ta kwakwalwar kwakwalwa. Wani lokaci STH qara qara saboda cututtuka irin na kwayoyin halitta:
- McCune-Albright Syndrome;
- hadaddun na Carney;
- Ciwo na Vermeer;
- iyalin da ke da dangi acromegaly.
Idan girma girman hormone ya ɗaga a cikin yaro, dalilin zai iya zama na wucin gadi dalilai:
- yawancin sunadarin gina jiki;
- m jiki aiki;
- yunwa;
- matsanancin barci;
- rage a cikin maida hankali akan sukari cikin jini;
- pathology na sha na na gina jiki a cikin hanji;
- damuwa.
Yaya za a rage girman hormone?
A farkon matakai na matsala ba tare da rikitarwa ba, ana bada magani na musamman. Hanyar da ta dace don rage girman kwayar cutar shi ne dauka ko yin amfani da kwayoyi wanda zai hana kwakwalwa da saki STG. Mafi yawan waɗannan kwayoyi suna dogara ne akan somatostatin. Yana da hormone wanda yake samar da hypothalamus. Ya rage mugunta daga cikin magungunan sunadarai da aka kwatanta da kuma taimakawa wajen normalize ta maida hankali cikin jini.
Yayin da hormone girma a cikin yaro ko babba ya haifar da ci gaban ƙwayar ƙwayar cuta a cikin kwakwalwa , za'a iya bada shawarar daɗaɗaɗɗen magani:
- M magani . A lokacin aikin, ana ci gaba da ƙwayar ƙwayar ko kuma an cire shi, wani lokacin - tare da karamin yanki na gland shine.
- Rashin iska. An yi amfani da shi a lokuta na musamman idan ba a yarda dashi ba.
An saukar da hormone girma
Rashin wannan abu ma yana da damuwa da matsalolin, amma ba ta da tsanani fiye da wuce haddi. Rashin daidaituwa na hormone girma a cikin manya ya haifar:
- kasawar tsoka;
- kiba;
- rashin tausayi;
- hanzari na tsufa;
- na kullum cututtukan zuciya na zuciya;
- rage libido;
- bakin ciki;
- tsofaffin maganganu;
- atherosclerosis.
Harshen tsire-tsire da aka saukar a cikin yara (ziyartar kwance) yana haifar da jinkirin cigaba ta jiki:
- low girma;
- kananan fasali;
- rage ƙafa da hannayensu;
- kodadde fata;
- murya mai murya;
- babu wasu halaye na jima'i na libido a lokacin yaro;
- marigayi na haila;
- musculature ba tare da ƙaddamarwa ba.
Me ya sa ake saukar da hormone girma?
Nisan nan na pituitary zai iya kasancewa da kuma samu. Sau da yawa yawan kwayoyin halitta da aka bincika an bayyana ta kwayoyin halitta, musamman idan an saukar da hormone mai girma a cikin yaro daga jariri. Wani abu kuma ya kasance daidai da halin da ake ciki tare da wucewar STH. Hakanan haɓakawa a cikin maida hankali ya haifar da ci gaban neoplasms a cikin yankin pituitary. Rashin girma hormone a cikin manya ana bincikar lafiya saboda dalilai masu zuwa:
- Harkokin aikin hannu na baya a kwakwalwa;
- shugaban sakawa a iska;
- cututtuka masu tsanani;
- craniocerebral rauni;
- endocrine rashin daidaituwa.
Yaya za a kara yawan hormone girma?
Don magance matsalar da aka bayyana, yana da muhimmanci a kafa abin da ya sa shi. Idan karuwa a cikin ciwon girma shine hormone ya kasance saboda ciwon kyamara a cikin glandon gwaninta, za'a buƙatar ta cire cirewa. A wasu lokuta, ana aiwatar da ƙaddamar da ƙwayar sinadaran ta hanyar mazan jiya. Magunguna na iya tabbatar da yanayin ci gaba da sauri, da magungunan da suke amfani dashi:
- Somatropin;
- Labaran;
- Rastan;
- Genotropin;
- Humatrop;
- Norditropin da analogues.
A cikin kula da yara yafi amfani da sauran kwayoyin da suka dace don dacewa da aikin glandar thyroid da balaga:
- estrogens;
- testosterone;
- glucocorticosteroids;
- progesterone;
- Ƙwararrun mayakanka.