Duk da ci gaban da aka samu na maganin da kuma nasarar da aka yiwa tsarin halittar mutum, ilimin cututtuka na rheumatoid ya kasance daya daga cikin cututtukan cututtukan da ke da wuya a magance su. Wannan farfadowa yana da asali na ainihi, ainihin dalilai na ci gaba ba a riga an kafa shi ba. Dangane da wannan, masana kimiyya sun kafa cibiyoyin bincike, suna ci gaba da inganta magungunan maganin arthritis na rheumatoid - magungunan sababbin mutanen da suke aiki fiye da wadanda suka riga su. Bugu da} ari, irin wa] annan jami'o'i ke haifar da mummunar tasiri a cikin marasa lafiya, mafi kyawun jurewa.
Shirye-shirye don maganin rheumatoid na yau da kullum
Sakamakon cutar da aka yi la'akari ya ƙunshi ƙungiyoyi biyu na magunguna:
- anti-mai kumburi ;
- asali.
An tsara nau'in magani na farko don saurin jin zafi a cikin gidajen abinci da sauran alamun alakar wutsiya, wanda yake da alamun bayyanar cututtuka.
Shirye-shiryen kayan aiki na jinkirin cigaba da ilimin lissafi ko canja hanyarsa zuwa gafartawa, ta tsara hanyoyin da ke tattare da ci gaba da cutar, ta kawar da aikin tsarin rigakafi.
A maimakon maganin magunguna, wanda ba kawai ya haifar da sakamako mai yawa ba, amma har yayi aiki sosai a hankali (a cikin wasu watanni), jami'o'in halittu sun zo. Shirye-shiryen aikin injiniya na kwayar cutar a cikin cututtuka na rheumatoid yana shafi aikin rigakafi, wato - hana samar da kwayoyin cytokine wanda ke haifar da matakan ƙananan ƙwayoyin cuta da lalata haɗin gwiwa. Babban amfani da jami'o'in nazarin halittu shine ikon su na aiki kawai a kan ƙungiya guda ɗaya na kayan aiki, ba tare da shafi sauran hanyoyin ba. Bugu da ƙari, irin waɗannan magunguna suna ba ka damar samun sakamako sosai fiye da yadda aka yi amfani da kwayoyi, an tabbatar da cewa an riga an riga an fara a cikin makonni 2-4 daga farkon shigarwa.
Magungunan injiniya na aikin injiniya don maganin cututtukan kwayoyin halitta sun haɗa da kwayoyi tare da kwayoyin cutar guda daya zuwa ga masu karɓar b-lymphocytes - wadanda ke cikin halaye na haɗuwa tare da haɗari. A gaskiya ma, magungunan da aka bayyana sun hana hana samar da cytokines, amma har yanzu a farkon farkon kafawarsu, "a cikin toho."
Jerin sababbin magunguna don maganin cututtuka na rheumatoid
Abubuwan da suka shafi nazarin halittu da aka yi la'akari da su a cikin sashe na baya zasu iya rarraba su cikin iri iri iri bisa ga tsarin aikin su. A yau, ana amfani da sababbin magunguna masu amfani da maganin rheumatoid:
1. Interleukin-1 masu hanawa:
- Kinneret (anakinra).
2. Blockers na tumo necrosis factor ko TNF-blockers:
- Alamar da aka yi (infliximab);
- Enbrel (tsinkaya);
- Humirae (adalimumab).
3. Yana nufin cewa tsangwama tare da aikin B-lymphocytes:
- Rituxan (rituximab).
4. Magunguna da suke hana ƙarar rigakafi T:
- Orence (abatacept).
A halin yanzu, ana samar da dukkanin magungunan da aka lissafa a waje kuma basu da wani analogues.
Shin sababbin kwayoyi sunyi tasiri akan ilimin cututtuka na rheumatoid?
Bisa ga binciken likita da sake dubawa da yawa ga masu ilimin rheumatologists, da marasa lafiya, kwayoyin da aka gabatar suna da sauri da kuma tabbatar da sakamako mai kyau har ma a cikin haɗar haɗar haɗari. Nazarin ya nuna cewa kashi daya cikin uku na mutanen da ke shan wahala daga ilimin cututtuka na rheumatoid yana ci gaba da yin gyaran cututtuka bayan amfani da magunguna.