17-OH haɗari ko 17-hydroxyprogesterone wani hormone steroid wanda aka haifar a cikin abin da ke ciki na gwanin adrenal kuma shine ainihin waɗannan kwayoyin hormones kamar cortisol, estradiol da testosterone. Haka kuma an samar da shi a cikin jima'i na jima'i, balagagge mai launi, jikin jiki da kuma ƙwayar cuta kuma a ƙarƙashin rinjayar kwayar cutar enzyme 17-20 ta juya zuwa jima'i na jima'i. Gaba, zamu yi la'akari da rawar da kwayar cutar 17 ke takawa a cikin jikin mace mai ciki da kuma ciki da kuma alamun rashin karuwarta da rashin ƙarfi.
Halittun halittu na hormone 17-oh progesterone
Kowane mutum na mataki na 17-OH yana cigaba cikin sa'o'i 24. Sabili da haka, ana lura da yawancin sauti a cikin safiya, da kuma ƙarami - a cikin dare. 17-OH na haɓaka a cikin mata ya bambanta dangane da lokaci na juyayi. Yawan ƙimar da aka yi a cikin wannan hormone an lura da shi a ranar jima'i na kwayar halitta (kafin a kara yawan haɓaka a hormone luteinizing). 17-OH na cigaba a cikin ɓangaren gaggawa yana raguwa da sauri, ta kai matakin mafi yawan lokaci a cikin lokaci.
Yanzu la'akari da dabi'u na al'ada na 17-OH, wanda ya danganta da lokaci na juyayi:
- a cikin lokaci na luteal - 0.99-11.51 nmol / l;
- a cikin lokaci mai banƙyama - 1,24-8,24 nmol / l;
- a cikin lokaci na jima'i - 0,91-4,24 nmol / l.
17-OH na cigaba da karuwa a cikin karuwa, yana kai yawan iyakarta a cikin 'yan makonni. Yayin da ake ciki, mahaifa kuma tana amsawa ga kira wannan hormone steroid. Ka yi la'akari da darajar da aka halatta na 17-OH a cikin lokacin ciki:
- a farkon farkon watanni uku - 3,55-17,03 nmol / l;
- a karo na biyu na uku - 3,55-20 nmol / l;
- a cikin na uku trimester - 3.75-33.33 nmol / l.
A premenopausal da kuma lokacin menopause, matakin hormone 17-OH progesterone yana raguwa sosai kuma ya kai 0.39-1.55 nmol / l.
Canji a matakin nauyin halayen 17-OH - ganewar asali da bayyanar cututtuka
Sakamakon rashin lafiya na 17-OH a cikin jini ya fi sau da yawa dalilin hypoplasia adrenal kuma za'a iya haɗuwa da rashin samar da sauran kwayoyin halitta. A cikin asibiti, zai iya nuna kanta a cikin hanyar cutar Addison, kuma yara sun kasa samar da cutar ta waje.
Ƙara yawan kwayar cutar ta 17-OH za a iya lura da ita ne kawai a cikin ciki, a wasu lokuta ya nuna alamun. Sabili da haka, haɓaka mai girma na 17-OH zai iya zama alamar bayyanar ciwon sukari, ovaries (magunguna masu kyau da polycystosis) da kuma cututtuka na kwayoyin cutar.
A cikin asibiti, za a iya ƙara yawan karuwa a cikin kwayar cutar 17-OH:
- cin zarafin dan lokaci;
- rashin haihuwa;
- maras lokaci daya abortions;
- babybird ko farkon mace-mace;
- da karuwa a cikin kwayar cutar 17-OH na iya nunawa ta hanyar kuraje (pimples);
- Idan an hawan sama da hamsin-hamsin hamsin na OH, za a iya tasowa da kwayar testosterone. Ana iya bayyana wannan a cikin nau'i na gashi a kan fuska da jiki (namiji gashi).
Za'a iya ƙaddamar da kwayar cutar 17-OH ta hanyar nazarin kwayar
Ta haka ne, mun bincika tasirin rayuwa a cikin jikin kwayoyin hormone 17-OH da kuma halaye masu halatta a cikin mata. Rage a cikin matakin wannan hormone zai iya kasancewa kawai a lokacin menopause, kuma yawancinsa yana dauke da al'ada cikin ciki. Canje-canje a cikin matakin 17-OH a wasu lokuta na iya kasancewa daya daga cikin alamun cututtuka na ciwon daji da cutar ovarian, wanda ke haifar da hyperandrogenism, rashin haihuwa ko kuma abortions.